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More than 80 cases of smallpox have been confirmed in at least 12 countries.
The World Health Organization has said another 50 suspected cases are being investigated - without mentioning any country - and warned that more cases are likely to be reported.
Infections have been confirmed in nine European countries, as well as in the US, Canada and Australia, writes the BBC .
The monkey line is most common in remote parts of Central and West Africa.
It is a rare viral infection, from which most people recover within a few weeks, according to the UK National Health Service.
The virus does not spread easily among people and the risk to the general public is said to be very low. There is no specific vaccine for monkeypox, but a smallpox vaccine offers 85% protection as the two viruses are quite similar.
So far, public health agencies in Europe have confirmed cases in the UK, Spain, Portugal, Germany, Belgium, France, the Netherlands, Italy and Sweden.